BMRB Entry 5940
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PDB ID:
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR5940
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Title: 1H, 15N and 13C backbone assignment of the carboxyl terminal domain of the cytokine binding module of the interleukin-6 receptor (IL-6R)
Deposition date: 2003-09-09 Original release date: 2004-07-06
Authors: Schwantner, Andreas; Dingley, Andrew; Ozbek, Suat; Rose-John, Stefan; Grotzinger, Joachim
Citation: Schwantner, Andreas; Dingley, Andrew; Ozbek, Suat; Hecht, Oliver; Rose-John, Stefan; Grotzinger, Joachim. "Letter to the Editor: 1H, 15N, 13C Backbone Assignment of the Carboxyl Terminal Domain of the Cytokine Binding Module of the Interleukin-6 Receptor" J. Biomol. NMR 29, 407-408 (2004).
Assembly members:
interleukin-6 receptor, polymer, 126 residues, 14500 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology
Entity Sequences (FASTA):
interleukin-6 receptor: MGILQPDPPANITVTAVARN
PRWLSVTWQDPHSWNSSFYR
LRFELRYRAERSKTFTTWMV
KDLQHHCVIHDAWSGLRHVV
QLRAQEEFGQGEWSEWSPEA
MGTPWTESRSPPAENEVSTP
MQALTT
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 360 |
| 13C chemical shifts | 393 |
| 15N chemical shifts | 103 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | interleukin-6 receptor | 1 |
Entities:
Entity 1, interleukin-6 receptor 126 residues - 14500 Da.
| 1 | MET | GLY | ILE | LEU | GLN | PRO | ASP | PRO | PRO | ALA | ||||
| 2 | ASN | ILE | THR | VAL | THR | ALA | VAL | ALA | ARG | ASN | ||||
| 3 | PRO | ARG | TRP | LEU | SER | VAL | THR | TRP | GLN | ASP | ||||
| 4 | PRO | HIS | SER | TRP | ASN | SER | SER | PHE | TYR | ARG | ||||
| 5 | LEU | ARG | PHE | GLU | LEU | ARG | TYR | ARG | ALA | GLU | ||||
| 6 | ARG | SER | LYS | THR | PHE | THR | THR | TRP | MET | VAL | ||||
| 7 | LYS | ASP | LEU | GLN | HIS | HIS | CYS | VAL | ILE | HIS | ||||
| 8 | ASP | ALA | TRP | SER | GLY | LEU | ARG | HIS | VAL | VAL | ||||
| 9 | GLN | LEU | ARG | ALA | GLN | GLU | GLU | PHE | GLY | GLN | ||||
| 10 | GLY | GLU | TRP | SER | GLU | TRP | SER | PRO | GLU | ALA | ||||
| 11 | MET | GLY | THR | PRO | TRP | THR | GLU | SER | ARG | SER | ||||
| 12 | PRO | PRO | ALA | GLU | ASN | GLU | VAL | SER | THR | PRO | ||||
| 13 | MET | GLN | ALA | LEU | THR | THR |
Samples:
sample_1: interleukin-6 receptor, [U-95% 13C; U-90% 15N], 1.0 mM
condition_1: pH: 5.0; temperature: 293 K
Experiments:
| Name | Sample | Sample state | Sample conditions |
|---|
Software:
No software information available
NMR spectrometers:
- Varian INOVA 600 MHz
Related Database Links:
| PDB | |
| DBJ | BAD97302 BAF85702 BAG35601 BAI46031 |
| EMBL | CAA31312 CAA41231 |
| GB | AAH89410 AAI32685 AAI32687 AAX36842 ABK41906 |
| PRF | 1502360A |
| REF | NP_000556 NP_852004 XP_001114404 XP_002810148 XP_003308452 |
| SP | P08887 |
Download simulated HSQC data in one of the following formats:
CSV: Backbone
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SPARKY: Backbone
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