BMRB Entry 19953
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PDB ID:
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full
BMRB Entry DOI: doi:10.13018/BMR19953
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Title: Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal Derived AGEs. PubMed: 24824951
Deposition date: 2014-05-05 Original release date: 2014-06-23
Authors: Shekhtman, Alexander; Xue, Jing; Ray, Rasmi; Singer, David; Bohme, David; Burz, David; Rai, Vivek; Hoffman, Ralf
Citation: Xue, Jing; Ray, Rasmi; Singer, David; Bohme, David; Burz, David; Rai, Vivek; Hoffman, Ralf; Shekhtman, Alexander. "The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs" Biochemistry 53, 3327-3335 (2014).
Assembly members:
V_domain, polymer, 105 residues, 11571.429 Da.
N~5~-[(2S,4S,5R)-4-hydroxy-5-methylimidazolidin-2-yl]-L-ornithine, non-polymer, 232.280 Da.
Natural source: Common Name: human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
V_domain: GSAQNITARIGEPLVLKCKG
APKKPPQRLEWKLNTGRTEA
WKVLSPQGGGPWDSVARVLP
NGSLFLPAVGIQDEGIFRCQ
AMNRNGKETKSNYRVRVYQI
PGKPE
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 623 |
| 13C chemical shifts | 345 |
| 15N chemical shifts | 92 |